SCHEMBL8495708

SCHEMBL8495708

CCCCCCCCCCCc1cc(C)cc(-n2ncc(-c3ccccc3)n2)c1O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 6/20 0.38
SOAT1 P35610 6/20 0.38
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TP53 P04637 1/20 0.36
SMPD1 P17405 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
TYR P14679 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HSD11B1 P28845 1/20 0.35
TLR8 Q9NR97 2/20 0.34
LIPG Q9Y5X9 1/20 0.34
STAT3 P40763 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8496224 1.00 SOAT2 (0.38) SOAT2SOAT1MAPTSMN1; SMN2TP53
SCHEMBL8496903 1.00 SOAT2 (0.38) SOAT2SOAT1MAPTSMN1; SMN2TP53
SCHEMBL8494899 1.00 SOAT2 (0.38) SOAT2SOAT1MAPTSMN1; SMN2TP53
SCHEMBL8495165 1.00 SOAT2 (0.38) SOAT2SOAT1MAPTSMN1; SMN2TP53
SCHEMBL8494857 1.00 SOAT2 (0.38) SOAT2SOAT1MAPTSMN1; SMN2TP53
SCHEMBL710157 0.80 NPC1 (0.56) MAPTSMN1; SMN2TP53TYRNPC1
SCHEMBL38926 0.80 NPC1 (0.56) MAPTSMN1; SMN2TP53TYRNPC1
SCHEMBL9628940 0.80 NPC1 (0.56) MAPTSMN1; SMN2TP53TYRNPC1
SCHEMBL10744136 0.80 NPC1 (0.56) MAPTSMN1; SMN2TP53TYRNPC1
SCHEMBL9628169 0.80 NPC1 (0.56) MAPTSMN1; SMN2TP53TYRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906908-A1 TRIAZINE DERIVATIVES AND RECORDING MATERIALS PREPARED THEREFROM NIPPON SODA CO., LTD. (JP) 1999-04-07 EP disclosed