Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499471 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL303522 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL8496647 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL273088 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL8496345 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL302640 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL302972 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL272185 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL303165 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 | |
| SCHEMBL302914 | 1.00 | SIGMAR1 (0.58) | SIGMAR1MAOAMAOBMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |