SCHEMBL272185

SCHEMBL272185

[CH2]CCCCCCCCCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 11/20 0.58
▸ MAOA P21397 1/20 0.56
▸ MAOB P27338 2/20 0.54
▸ MAPT P10636 1/20 0.54
▸ RXFP1 Q9HBX9 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8499471 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL303522 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL8496647 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL273088 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL8496345 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL8497072 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL302640 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL302972 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL303165 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL302914 1.00 SIGMAR1 (0.58) SIGMAR1MAOAMAOBMAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 857 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3676240-B1 ESTER COMPOUNDS AND LUBRICATING OIL COMPOSITIONS CONTAINING SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-01 — — EP claimed
CN-111032613-B Ester compound, lubricating oil composition containing the same, and method for producing the same 埃克森美孚化学专利公司 2023-03-28 — — CN claimed
EP-3688125-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME ExxonMobil Chemical Patents Inc. (US) 2020-08-05 — — EP claimed
EP-3676240-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME ExxonMobil Chemical Patents Inc. (US) 2020-07-08 — — EP claimed
CN-111344386-A Ester compound, lubricating oil composition containing same, and method for producing same 埃克森美孚化学专利公司 2020-06-26 — — CN claimed
US-10683464-B2 Ester compounds, lubricating oil compositions containing same and processes for making same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-06-16 — — US claimed
US-10662388-B2 Ester compounds, lubricating oil compositions containing same and processes for making same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-05-26 — — US claimed
CN-111032613-A Ester compound, lubricating oil composition containing the same, and process for producing the same 埃克森美孚化学专利公司 2020-04-17 — — CN claimed
WO-2019067060-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-04-04 — — WO claimed
US-20190100711-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-04-04 — — US claimed
CN-102427816-A Pharmaceutical composition for treating or preventing eye diseases UBE INDUSTRIES 2012-04-25 — — CN claimed
US-20120095215-A1 MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF EYE DISEASES UBE INDUSTRIES, LTD. (JP) 2012-04-19 — — US claimed
EP-2415474-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF OPHTHALMIC DISEASES Ube Industries, Ltd. (JP) 2012-02-08 — — EP claimed
CN-101861319-A Benzazepinone compound UBE INDUSTRIES 2010-10-13 — — CN claimed
US-20100249396-A1 BENZAZEPINONE COMPOUND UBE INDUSTRIES, LTD. (JP) 2010-09-30 — — US claimed
EP-2221308-A1 BENZAZEPINONE COMPOUND Ube Industries, Ltd. (JP) 2010-08-25 — — EP claimed
US-20070191583-A1 Polymers based on 3,6-and 2,7-conjugated poly(phenanthrene) and pled devices MAX-PLANCK-SOCIETY (DE) 2007-08-16 — — US claimed
US-20070152209-A1 Devices using polymers based on 3,6- and 2,7-conjugated poly(phenanthrene) E. I. DU PONT DE NEMOURS AND COMPANY 2007-07-05 — — US claimed
US-5780633-A Process for the preparation of indolizine derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-14 — — US claimed
EP-0260689-A2 Naphtholactam quadratic-acid dyes and optical registration materials containing them BASF Aktiengesellschaft (DE) 1988-03-23 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095215-A1 MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF EYE DISEASES VEGFA, UACA, PGF SIGMAR1 2362/4885MAOA 1590/4885MAOB 957/4885
US-20100249396-A1 BENZAZEPINONE COMPOUND KCNJ11, KCNJ1, KCNJ2 SIGMAR1 170/4885MAOA 730/4885MAOB 299/4885
US-10662388-B2 Ester compounds, lubricating oil compositions containing same and processes for making same GK, NOTUM, EBP SIGMAR1 976/4885MAOA 4049/4885MAOB 3353/4885
US-20190100711-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same ELOVL1, ELOVL5, ELOVL3 SIGMAR1 2171/4885MAOA 2331/4885MAOB 2806/4885
US-10683464-B2 Ester compounds, lubricating oil compositions containing same and processes for making same ELOVL1, ELOVL5, ELOVL3 SIGMAR1 2171/4885MAOA 2331/4885MAOB 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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