Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 11/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646329 | 0.94 | HPN (0.59) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL648287 | 0.87 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11741056 | 0.81 | HPN (0.49) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL647467 | 0.80 | ALOX15 (0.68) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11742489 | 0.80 | HPN (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL8496245 | 0.78 | ALOX15 (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL8491962 | 0.78 | ALOX15 (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11555358 | 0.78 | ALOX15 (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9504479 | 0.78 | ALOX15 (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL647768 | 0.77 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152022-B1 | DI-(SUBSTITUTED HYDROXYPHENYLTHIO)-ALKANES AND CYCLOALKANES AND COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | claimed |
| US-4611023-A | Di-(substituted hydroxyphenylthio) alkane and cycloalkane stabilizers and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1986-09-09 | — | — | US | claimed |
| EP-0152022-A2 | Di-(substituted hydroxyphenylthio)-alkanes and cycloalkanes and compositions containing them | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| US-5981603-A | Antiviral agents | VYREX CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| US-5874478-A | ADMINISTERING A HYDROXYBENZYL THIO ALKYL OR ARYL AS ANTITUMOR AGENTS, VIRICIDES | VYREX CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0482071-B1 | NEW ANTIVIRAL AGENTS | BIODOR US HOLDING CORP (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0152022-B1 | DI-(SUBSTITUTED HYDROXYPHENYLTHIO)-ALKANES AND CYCLOALKANES AND COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| US-4611023-A | Di-(substituted hydroxyphenylthio) alkane and cycloalkane stabilizers and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0152022-A2 | Di-(substituted hydroxyphenylthio)-alkanes and cycloalkanes and compositions containing them | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | disclosed |