Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 16/20 | 0.73 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497161 | 1.00 | G6PC1 (0.73) | G6PC1GRIN1GRIN2BLMNAMAPT | |
| SCHEMBL8498716 | 0.90 | G6PC1 (0.76) | G6PC1GRIN1GRIN2BLMNAMAPT | |
| SCHEMBL8498717 | 0.90 | G6PC1 (0.76) | G6PC1GRIN1GRIN2BLMNAMAPT | |
| SCHEMBL8498660 | 0.90 | G6PC1 (0.74) | G6PC1GRIN1GRIN2B | |
| SCHEMBL8498656 | 0.90 | G6PC1 (0.74) | G6PC1GRIN1GRIN2B | |
| SCHEMBL8495003 | 0.87 | G6PC1 (0.78) | G6PC1MAPTMAPK1 | |
| SCHEMBL8495006 | 0.87 | G6PC1 (0.78) | G6PC1MAPTMAPK1 | |
| SCHEMBL8496820 | 0.85 | G6PC1 (0.52) | G6PC1GRIN1GRIN2BLMNAMAPT | |
| SCHEMBL8496822 | 0.85 | G6PC1 (0.52) | G6PC1GRIN1GRIN2BLMNAMAPT | |
| SCHEMBL8499080 | 0.85 | G6PC1 (1.00) | G6PC1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |