Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 13/20 | 0.66 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339707 | 1.00 | P4HB (0.66) | P4HBMAOAMAOBFBP1CYP1A2 | |
| SCHEMBL1225943 | 0.88 | P4HB (0.64) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL30745014 | 0.88 | P4HB (0.64) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL30912094 | 0.88 | P4HB (0.64) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL1225940 | 0.88 | P4HB (0.64) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL6977108 | 0.86 | P4HB (0.62) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL4359926 | 0.86 | P4HB (0.62) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL6977115 | 0.86 | P4HB (0.62) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL4101470 | 0.86 | P4HB (0.62) | P4HBMAOAMAOBFBP1 | |
| Hydrochloric Acid SCHEMBL4101473 | 0.86 | P4HB (0.62) | P4HBMAOAMAOBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-B1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5717109-A | CARBOXYCYCLOPROPYL GLYCINE DERIVATIVES; USEFUL FOR TREATMENT OF ACUTE OR CHRONIC NEURODEGENERATIVE CONDITIONS, AND AS ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC, ANXIOLYTIC, ANTIDEPRESSANT AND ANTI-EMETIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |