Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 14/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912094 | 1.00 | P4HB (0.64) | P4HBNPSR1MAOAMAOBFBP1 | |
| SCHEMBL1225943 | 1.00 | P4HB (0.64) | P4HBNPSR1MAOAMAOBFBP1 | |
| SCHEMBL30745014 | 1.00 | P4HB (0.64) | P4HBNPSR1MAOAMAOBFBP1 | |
| Hydrochloric Acid SCHEMBL4101473 | 0.98 | P4HB (0.62) | P4HBNPSR1MAOAMAOBFBP1 | |
| SCHEMBL8497675 | 0.88 | P4HB (0.66) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL7339707 | 0.88 | P4HB (0.66) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL9168215 | 0.87 | P4HB (0.56) | P4HBNPSR1MAOAMAOB | |
| SCHEMBL9168213 | 0.87 | P4HB (0.56) | P4HBNPSR1MAOAMAOB | |
| SCHEMBL8148520 | 0.85 | P4HB (0.62) | P4HBMAOAMAOBFBP1 | |
| SCHEMBL4101470 | 0.85 | P4HB (0.62) | P4HBMAOAMAOBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-3470407-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2024-01-24 | — | — | EP | disclosed |
| US-11872202-B2 | Pleuromutilin cinnamic acid ester compounds with activities against antibiotic-resistant infections | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2024-01-16 | — | — | US | disclosed |
| EP-3704113-B1 | BRIDGED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-10-11 | — | — | EP | disclosed |
| US-20230172889-A1 | PLEUROMUTILIN CINNAMIC ACID ESTER COMPOUNDS WITH ACTIVITIES AGAINST ANTIBIOTIC-RESISTANT INFECTIONS | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-06-08 | — | — | US | disclosed |
| CN-114230519-A | Pleuromutilin cinnamate compounds with drug-resistant bacterium resisting activity and synthesis method and application thereof | 陕西科技大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-110248971-B | Copolymer and optical film using the same | 东曹株式会社 | 2021-11-02 | — | — | CN | disclosed |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
| US-10730863-B2 | Bridged bicyclic compounds as farnesoid X receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-04 | — | — | US | disclosed |
| CN-111295382-A | Bridged bicyclic compounds as modulators of farnesoid X receptors | 百时美施贵宝公司 | 2020-06-16 | — | — | CN | disclosed |
| US-4845110-A | Organic compounds and their pharmaceutical use | LILLY INDUSTRIES LIMITED (GB) | 1989-07-04 | — | — | US | disclosed |
| EP-0134111-B1 | ARALIPHATIC SULPHIDES,SULPHONES AND SULPHOXIDES AND THEIR PHARMACEUTICAL USE | Lilly Industries Limited (GB) | 1988-12-07 | — | — | EP | disclosed |
| EP-0235452-A2 | Organic compounds and their pharmaceutical use | LILLY INDUSTRIES LIMITED (GB) | 1987-09-09 | — | — | EP | disclosed |
| US-4665189-A | LEUKOTRIENE ANTAGONISTS | LILLY INDUSTRIES LIMITED (GB) | 1987-05-12 | — | — | US | disclosed |
| EP-0201823-A2 | Novel intermediates for the production of pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1986-11-20 | — | — | EP | disclosed |
| EP-0186426-A2 | Tetrazolyl compounds and their pharmaceutical use | Lilly Industries Limited (GB) | 1986-07-02 | — | — | EP | disclosed |
| EP-0134111-A1 | Araliphatic sulphides,sulphones and sulphoxides and their pharmaceutical use | Lilly Industries Limited (GB) | 1985-03-13 | — | — | EP | disclosed |
| EP-0052921-B1 | METHODS AND COMPOSITIONS FOR ASSAYING FOR THE PRODUCTION OF 1,4-DIHYDROPYRIDYL | SYVA COMPANY (US) | 1984-06-13 | — | — | EP | disclosed |
| US-4404278-A | RADIOIMMUNOLOGY; FLUORESCENCE; ANTIBODIES | SYVA COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0052921-A1 | Methods and compositions for assaying for the production of 1,4-dihydropyridyl | SYVA COMPANY (US) | 1982-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | P4HB 2561/4885NPSR1 241/4885MAOA 1453/4885 |
| US-20230172889-A1 | PLEUROMUTILIN CINNAMIC ACID ESTER COMPOUNDS WITH ACTIVITIES AGAINST ANTIBIOTIC-RESISTANT INFECTIONS | RELA, PLEC, ABL1 | P4HB 420/4885NPSR1 1945/4885MAOA 3399/4885 |
| US-10730863-B2 | Bridged bicyclic compounds as farnesoid X receptor modulators | NR1H4, FXR1, NR1H2 | P4HB 2276/4885NPSR1 570/4885MAOA 4098/4885 |
| US-11872202-B2 | Pleuromutilin cinnamic acid ester compounds with activities against antibiotic-resistant infections | RELA, PLEC, ABL1 | P4HB 420/4885NPSR1 1945/4885MAOA 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.