Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498438 | 1.00 | G6PC1 (0.54) | G6PC1MEN1KMT2AKDM4EGAA | |
| SCHEMBL8497704 | 0.89 | MEN1 (0.66) | G6PC1MEN1KMT2AKDM4EGAA | |
| SCHEMBL8497706 | 0.89 | MEN1 (0.66) | G6PC1MEN1KMT2AKDM4EGAA | |
| SCHEMBL8495136 | 0.88 | G6PC1 (0.64) | G6PC1KMT2AHTTNPC1RAB9A | |
| SCHEMBL8495137 | 0.88 | G6PC1 (0.64) | G6PC1KMT2AHTTNPC1RAB9A | |
| SCHEMBL8498925 | 0.74 | G6PC1 (0.70) | G6PC1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8498931 | 0.74 | G6PC1 (0.70) | G6PC1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4257063 | 0.73 | PTPN1 (0.75) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL4257060 | 0.73 | PTPN1 (0.75) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL8495185 | 0.71 | G6PC1 (1.00) | G6PC1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | claimed |