Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.64 |
| ▸ | DRD4 | P21917 | 7/20 | 0.64 |
| ▸ | DRD3 | P35462 | 5/20 | 0.64 |
| ▸ | HTR1A | P08908 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703066 | 0.85 | DRD2 (0.85) | DRD2DRD4DRD3HTR1AADRA1A | |
| SCHEMBL10722398 | 0.79 | HPGD (0.67) | — | |
| SCHEMBL14761584 | 0.79 | DRD2 (0.94) | DRD2DRD4DRD3HTR1AADRA1A | |
| SCHEMBL1388189 | 0.79 | DRD2 (0.72) | DRD2DRD4DRD3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8980926 | 0.78 | DRD2 (0.70) | DRD2DRD4DRD3SLC6A2SLC6A4 | |
| SCHEMBL14761722 | 0.78 | DRD2 (1.00) | DRD2DRD4DRD3HTR1AADRA1A | |
| SCHEMBL10911336 | 0.78 | DRD2 (1.00) | DRD2DRD4DRD3HTR1AADRA1A | |
| SCHEMBL1388131 | 0.77 | OPRK1 (0.61) | DRD2DRD4DRD3ADRA1ASLC6A2 | |
| SCHEMBL14761605 | 0.77 | DRD2 (0.98) | DRD2DRD4DRD3HTR1AADRA1A | |
| Hydrochloric Acid SCHEMBL8980954 | 0.77 | OPRK1 (0.60) | DRD2DRD4DRD3ADRA1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11080119-A | — | — | None | — | — | JP | disclosed |
| JP-H1180119-A | PIPERAZINE DERIVATIVE | SANKYO CO LTD | 1999-03-26 | — | — | JP | disclosed |