SCHEMBL8498658

SCHEMBL8498658

[CH]=CC(CC(C)CCCC)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547802 0.85 CA2 (0.33) CA2
SCHEMBL8510537 0.82 CA2 (0.32) CA2
SCHEMBL9410229 0.82 CA2 (0.32) CA2
SCHEMBL6652531 0.82 CA2 (0.32) CA2
SCHEMBL6652536 0.82 CA2 (0.32) CA2
SCHEMBL8510540 0.82 CA2 (0.32) CA2
SCHEMBL9410232 0.82 CA2 (0.32) CA2
SCHEMBL8899734 0.81 CA2 (0.36) CA2
SCHEMBL8907786 0.76 CA2 (0.33) CA2
SCHEMBL8907920 0.76 CA2 (0.33) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0295880-B1 Substituted cyclic ketones, substituted cyclic enones, and process for producing the same NISSAN CHEMICAL IND LTD (JP) 1999-01-07 EP claimed
US-5227505-A Chemical intermediates for prostaglandins NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1993-07-13 US claimed
EP-0295880-B1 Substituted cyclic ketones, substituted cyclic enones, and process for producing the same NISSAN CHEMICAL IND LTD (JP) 1999-01-07 EP disclosed
US-5675031-A 4-hydroxy-2-cyclopentenone derivatives and anticancer agent and bone formation accelerator containing the same TEIJIN LIMITED (JP) 1997-10-07 US disclosed
EP-0448726-B1 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LTD (JP) 1996-04-24 EP disclosed
EP-0659728-A1 4-HYDROXY-2-CYCLOPENTENONE DERIVATIVE AND CARCINOSTATIC AND OSTEOGENESIS PROMOTER CONTAINING THE SAME TEIJIN LIMITED (JP) 1995-06-28 EP disclosed
US-5338844-A 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient TEIJIN LIMITED (JP) 1994-08-16 US disclosed
US-5254708-A Intermediates for pharmaceuticals, agricultural chemicals, prostaglandins NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-19 US disclosed
US-5231208-A Prostaglandin intermediate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1993-07-27 US disclosed
US-5227505-A Chemical intermediates for prostaglandins NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1993-07-13 US disclosed
US-5216183-A Antitumor, anticarcinogenic agents; bone formation accelerators TEIJIN LIMITED (JP) 1993-06-01 US disclosed
US-5089625-A SUBSTITUTED CYCLIC KENTONES, SUBSTITUTED CYCLIC ENONES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1992-02-18 US disclosed
EP-0448726-A1 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1991-10-02 EP disclosed
US-4994619-A Intermediates for prostaglandins NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1991-02-19 US disclosed
EP-0295880-A1 Substituted cyclic ketones, substituted cyclic enones, and process for producing the same NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-12-21 EP disclosed