Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499001 | 1.00 | MEN1 (0.57) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL170359 | 0.94 | MEN1 (0.62) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8499198 | 0.94 | MEN1 (0.62) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8497068 | 0.92 | G6PC1 (0.60) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8497067 | 0.92 | G6PC1 (0.60) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL28045556 | 0.88 | MAPT (0.58) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13655507 | 0.87 | G6PC1 (0.55) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL14342245 | 0.87 | G6PC1 (0.55) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL14410991 | 0.80 | RELA (0.53) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8494526 | 0.79 | MAPT (0.57) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |