Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 9/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PDE6A | P16499 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498267 | 0.91 | G6PC1 (0.51) | G6PC1GRIN2BTSHRCYP2A6 | |
| SCHEMBL8493516 | 0.87 | CYP2A6 (0.39) | TSHRCYP1A2DRD3KMT2ACYP2A6 | |
| SCHEMBL8498371 | 0.81 | LRRK2 (0.42) | G6PC1GRIN2BTSHRLMNAKMT2A | |
| SCHEMBL14799680 | 0.77 | G6PC1 (0.53) | G6PC1TSHR | |
| SCHEMBL14799400 | 0.73 | G6PC1 (0.51) | G6PC1TSHR | |
| SCHEMBL14799399 | 0.73 | G6PC1 (0.51) | G6PC1TSHR | |
| SCHEMBL8499655 | 0.73 | GAA (0.35) | G6PC1LMNAKMT2ALRRK2POLB | |
| SCHEMBL8498988 | 0.70 | G6PC1 (0.84) | G6PC1LMNAKMT2ACYP2A6LRRK2 | |
| SCHEMBL8498991 | 0.70 | G6PC1 (0.84) | G6PC1LMNAKMT2ACYP2A6LRRK2 | |
| SCHEMBL15439235 | 0.69 | G6PC1 (0.46) | G6PC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | claimed |