Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.32 |
| ▸ | MEN1 | O00255 | 6/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498371 | 0.84 | LRRK2 (0.42) | GAAMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL8499167 | 0.77 | ALDH1A1 (0.50) | GAAKDM4EALDH1A1MAPK1RECQL | |
| SCHEMBL8499169 | 0.77 | ALDH1A1 (0.50) | GAAKDM4EALDH1A1MAPK1RECQL | |
| SCHEMBL8498249 | 0.76 | GAA (0.51) | GAAMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL8498244 | 0.76 | GAA (0.51) | GAAMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL8499104 | 0.73 | G6PC1 (0.45) | LRRK2KMT2APOLBG6PC1LMNA | |
| SCHEMBL8493516 | 0.70 | CYP2A6 (0.39) | ALDH1A1LRRK2KMT2AMEN1 | |
| SCHEMBL8498267 | 0.69 | G6PC1 (0.51) | ALDH1A1G6PC1 | |
| SCHEMBL8499830 | 0.65 | KDM4E (0.47) | GAAKDM4EALDH1A1RECQLKMT2A | |
| SCHEMBL8499831 | 0.65 | KDM4E (0.47) | GAAKDM4EALDH1A1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |