Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499909 | 0.91 | FFAR1 (0.45) | PSMB5FFAR1PPARGFFAR4PLA2G10 | |
| SCHEMBL8501202 | 0.80 | FFAR1 (0.51) | FFAR1FFAR4HPN | |
| Hydrochloric Acid SCHEMBL8503259 | 0.80 | PTGDR2 (0.45) | FFAR1FFAR4 | |
| Hydrochloric Acid SCHEMBL8888409 | 0.72 | FFAR1 (0.50) | FFAR1FFAR4 | |
| SCHEMBL334758 | 0.71 | FFAR1 (0.68) | FFAR1PLA2G10 | |
| SCHEMBL20515320 | 0.70 | PSMB5 (1.00) | PSMB5 | |
| SCHEMBL8499164 | 0.70 | PDGFRB (0.52) | FFAR1LMNA | |
| SCHEMBL8504167 | 0.68 | CDK8 (0.47) | LMNA | |
| SCHEMBL11827265 | 0.66 | MTNR1A (0.53) | FFAR1FFAR4LMNA | |
| SCHEMBL24307632 | 0.66 | FFAR1 (0.73) | FFAR1FFAR4PLA2G10PLA2G2ASLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36256-E | ADMINISTERING ARYL-SUBSTITUTED QUINOXALINE DERIVATIVES AS ANTIPROLIFERATIVE, ANTICARCINOGENIC AND ANTITUMOR AGENTS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| US-5795889-A | INHIBITING CELL GROWTH WITH ENZYME INHIBITORS FOR SKIN DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-08-18 | — | — | US | disclosed |