SCHEMBL8499306

SCHEMBL8499306

CCCc1ccc(OS(=O)(=O)c2ccccc2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 2/20 0.50
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ALPL P05186 3/20 0.44
METAP2 P50579 2/20 0.43
FFAR4 Q5NUL3 2/20 0.43
HTT P42858 1/20 0.42
PTPN1 P18031 1/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 3/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CNR2 P34972 1/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 1/20 0.40
KAT6A Q92794 1/20 0.40
METAP1 P53582 1/20 0.40
ENPP2 Q13822 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8499431 0.89 ALPI (0.53) ALPIALPLFFAR4ALDH1A1MAPT
SCHEMBL8503078 0.88 SMN1; SMN2 (0.52) ALPISMN1; SMN2NPC1RAB9AALPL
SCHEMBL3845366 0.87 SMN1; SMN2 (0.47) ALPISMN1; SMN2NPC1RAB9AALPL
SCHEMBL8499435 0.84 MEN1 (0.46) ALPISMN1; SMN2METAP2FFAR4HTT
SCHEMBL5672258 0.81 TDP1 (0.48) ALPISMN1; SMN2NPC1RAB9AALPL
SCHEMBL8503123 0.80 FFAR4 (0.44) ALPISMN1; SMN2ALPLFFAR4HTT
SCHEMBL3212332 0.77 ALDH1A1 (0.48) ALPISMN1; SMN2NPC1RAB9AFFAR4
SCHEMBL8837781 0.77 TDP1 (0.57) ALPISMN1; SMN2NPC1RAB9AALPL
SCHEMBL10180574 0.77 HTT (0.50) ALPISMN1; SMN2NPC1RAB9AALPL
SCHEMBL29673571 0.77 METAP2 (0.52) SMN1; SMN2NPC1RAB9AMETAP2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956312-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR Corporation (JP) 1999-11-17 EP disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed