Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511456 | 0.90 | OGA (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3861569 | 0.90 | OGA (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3861567 | 0.90 | OGA (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL7951153 | 0.85 | NPC1 (0.51) | RAB9ANPC1TP53GLAALDH1A1 | |
| SCHEMBL6561480 | 0.82 | FFAR1 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8249411 | 0.81 | RAB9A (0.50) | RAB9ANPC1OGAALDH1A1KDM4E | |
| SCHEMBL3144643 | 0.81 | RAB9A (0.50) | RAB9ANPC1OGAALDH1A1KDM4E | |
| SCHEMBL15239118 | 0.81 | RAB9A (0.50) | RAB9ANPC1OGAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL131112 | 0.80 | RAB9A (0.49) | RAB9ANPC1OGAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4585660 | 0.80 | RAB9A (0.49) | RAB9ANPC1OGAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447038-B2 | Substituted B-amino acid derivatives as CXCR3 receptor antagonists | SANOFI (FR) | 2016-09-20 | — | — | US | disclosed |
| US-9447038-B2 | Substituted B-amino acid derivatives as CXCR3 receptor antagonists | SANOFI (FR) | 2016-09-20 | — | — | US | disclosed |
| EP-2852578-B1 | SUBSTITUTED ß-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | SANOFI SA (FR) | 2016-04-27 | — | — | EP | disclosed |
| US-20150073004-A1 | SUBSTITUTED B-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2015-03-12 | — | — | US | disclosed |
| US-20150073004-A1 | SUBSTITUTED B-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2015-03-12 | — | — | US | disclosed |
| WO-2013174485-A1 | SUBSTITUTED ß-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2013-11-28 | — | — | WO | disclosed |
| EP-1189881-B2 | PROPANOIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2013-01-23 | — | — | EP | disclosed |
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073004-A1 | SUBSTITUTED B-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | CXCR3, CXCR1, CXCR2 | HDAC3 3092/4885HDAC4 4715/4885HDAC1 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.