Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | FCER2 | P06734 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16414920 | 0.94 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL8499487 | 0.83 | CYP1A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL16414412 | 0.82 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL15351813 | 0.81 | NAAA (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL8253244 | 0.81 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL8430543 | 0.80 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL9718376 | 0.80 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL8499350 | 0.80 | KDM4E (0.45) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL16414546 | 0.79 | NAAA (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 | |
| SCHEMBL15352131 | 0.79 | NAAA (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |