SCHEMBL8499487

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15351724	0.93	CYP1A2 (0.50)	CYP1A2CYP2A6CYP19A1DAOSLC6A2
	SCHEMBL8499344	0.83	SLC6A2 (0.45)	CYP1A2CYP2A6CYP19A1DAOSLC6A2
	SCHEMBL11743633	0.79	CYP19A1 (0.45)	CYP1A2CYP2A6CYP19A1DAOSLC6A2
	SCHEMBL8499490	0.78	CYP1A2 (0.48)	CYP1A2CYP2A6CYP19A1DAOSLC6A2
	SCHEMBL6959233	0.78	CYP1A2 (0.48)	CYP1A2CYP2A6CYP19A1DAOSLC6A2
	SCHEMBL14604942	0.78	CYP1A2 (0.59)	CYP1A2CYP2A6CYP19A1DAOSLC6A2
	SCHEMBL6233504	0.78	LOXL2 (0.56)	CYP1A2CYP2A6CYP19A1DAOSLC6A2
	SCHEMBL29936739	0.78	CYP1A2 (0.72)	CYP1A2CYP2A6CYP19A1DAOSLC6A4
	SCHEMBL6564751	0.78	CYP1A2 (0.72)	CYP1A2CYP2A6CYP19A1DAOSLC6A4
	SCHEMBL16414920	0.77	SLC6A2 (0.50)	CYP1A2CYP2A6CYP19A1DAOSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.