Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19468088 | 0.83 | SLC6A4 (0.49) | SLC6A4KMT2AALDH1A1HTR2AHTR1A | |
| SCHEMBL8120073 | 0.80 | TACR1 (0.54) | — | |
| SCHEMBL8499278 | 0.80 | ALDH1A1 (0.45) | SLC6A4KMT2AALDH1A1HPGDHTT | |
| SCHEMBL3447596 | 0.80 | SLC6A4 (0.52) | SLC6A4KMT2AALDH1A1GLAHTR2A | |
| SCHEMBL7828310 | 0.76 | DNMT1 (0.61) | SLC6A4MC4RHTR2AHTR1AADRA2A | |
| SCHEMBL8496222 | 0.76 | HRH3 (0.43) | SLC6A4KMT2AMTNR1A | |
| SCHEMBL1258065 | 0.76 | DNMT1 (0.61) | SLC6A4MC4RHTR2AHTR1AADRA2A | |
| SCHEMBL7945345 | 0.74 | HTR3E (0.53) | KMT2AALDH1A1 | |
| SCHEMBL4317754 | 0.72 | POLB (0.49) | SLC6A4KMT2AALDH1A1HPGD | |
| SCHEMBL6132884 | 0.72 | POLB (0.49) | SLC6A4KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | disclosed |