Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 10/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016879 | 0.88 | DRD2 (0.50) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL30958873 | 0.88 | DRD2 (0.50) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL9016864 | 0.88 | DRD2 (0.50) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL9016867 | 0.88 | DRD2 (0.50) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL9022884 | 0.88 | MAOA (0.46) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL9207106 | 0.86 | DRD2 (0.52) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL9023739 | 0.83 | MAOB (0.43) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL9016866 | 0.82 | MAOA (0.44) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL9016863 | 0.82 | MAOA (0.44) | MAOAMAOBDRD2DRD3HTR2A | |
| SCHEMBL8705136 | 0.78 | DRD2 (0.38) | DRD2DRD3DRD4PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11001482-A | — | — | None | — | — | JP | disclosed |
| JP-H111482-A | CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1999-01-06 | — | — | JP | disclosed |