Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816463 | 0.79 | KDM4E (0.45) | KDM4EPKMHRH3MEN1KMT2A | |
| SCHEMBL18622068 | 0.73 | PKM (0.45) | KDM4EPKMHRH3MEN1KMT2A | |
| SCHEMBL26694736 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL7156032 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL4561796 | 0.72 | TSHR (0.35) | — | |
| SCHEMBL3402649 | 0.71 | PKM (0.36) | KDM4EPKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3485811 | 0.69 | NAALAD2 (0.41) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15796366 | 0.69 | HRH3 (0.61) | HRH3MEN1KMT2A | |
| SCHEMBL14136486 | 0.68 | PKM (0.41) | KDM4EPKM | |
| SCHEMBL8585464 | 0.68 | MAPT (0.38) | KDM4EPKMMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |