Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18622068 | 0.87 | PKM (0.45) | KDM4EPKMHRH3CA2PTGS1 | |
| SCHEMBL14136486 | 0.81 | PKM (0.41) | KDM4EPKMTHRBHTTMAPT | |
| SCHEMBL20388578 | 0.79 | PKM (0.40) | KDM4EPKMHRH3THRBHTT | |
| SCHEMBL21780327 | 0.79 | PKM (0.40) | KDM4EPKMHRH3THRBHTT | |
| SCHEMBL17175154 | 0.79 | PKM (0.44) | KDM4EPKMTHRBHTTL3MBTL1 | |
| SCHEMBL8500067 | 0.79 | KDM4E (0.36) | KDM4EPKMHRH3MEN1KMT2A | |
| SCHEMBL221667 | 0.78 | HRH3 (0.35) | KDM4EPKMHRH3L3MBTL1GLA | |
| SCHEMBL14733226 | 0.78 | HTT (0.41) | KDM4EPKMHRH3PTGS1THRB | |
| SCHEMBL14366070 | 0.77 | KDM4E (0.40) | KDM4EPKMCA2PTGS1MMP12 | |
| SCHEMBL14733163 | 0.76 | MEN1 (0.51) | KDM4EPKMHRH3THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945560-B | GPR119 agonists | 卡尔优普公司 | 2024-08-13 | — | — | CN | claimed |
| CN-114945560-A | GPR119 agonists | 卡尔优普公司 | 2022-08-26 | — | — | CN | claimed |
| CN-108602759-B | Method for preparing a composition of alkanolamine alkylamide and polyol | 阿克苏诺贝尔化学品国际有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-11672867-B2 | Protein-templated self-assembly of a covalent polymer network for intracellular trafficking and traceless release | UNIVERSITY OF MASSACHUSETTS (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230135432-A1 | POLYMERIC NANOPARTICLES AND DERIVATIVES THEREOF FOR NUCLEIC ACID BINDING AND DELIVERY | UNIV MASSACHUSETTS (US) | 2023-05-04 | — | — | US | disclosed |
| US-11572427-B2 | Hydrophilic polymeric particles and methods for making and using same | Life Technologies Corporation (US) | 2023-02-07 | — | — | US | disclosed |
| CN-114945560-A | GPR119 agonists | 卡尔优普公司 | 2022-08-26 | — | — | CN | disclosed |
| EP-3125033-B1 | LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-20210155726-A1 | HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING AND USING SAME | LIFE TECHNOLOGIES AS (NO) | 2021-05-27 | — | — | US | disclosed |
| US-10782566-B2 | Liquid crystal display device | JNC CORPORATION (JP) | 2020-09-22 | — | — | US | disclosed |
| US-20200282066-A1 | PROTEIN-TEMPLATED SELF-ASSEMBLY OF A COVALENT POLYMER NETWORK FOR INTRACELLULAR TRAFFICKING AND TRACELESS RELEASE | UNIV MASSACHUSETTS (US) | 2020-09-10 | — | — | US | disclosed |
| US-8263754-B2 | Amphiphiles for protein solubilization and stabilization | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-09-11 | — | — | US | disclosed |
| US-20110269806-A1 | 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS | PHARMACYCLICS, INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20100055068-A1 | GRAFTED POLYMERS AND USES THEREOF | INTERFACE BIOLOGICS INCORPORATED (CA) | 2010-03-04 | — | — | US | disclosed |
| US-20090270598-A1 | AMPHIPHILES FOR PROTEIN SOLUBILIZATION AND STABILIZATION | WARF - WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090054432-A1 | 2-(2-Hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-Carboxamidine Derivatives as Factor VIIA Inhibitors | PHARMACYLICS, INC. A DELAWARE CORPORATION (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2007148230-A2 | GRAFTED POLYMERS AND USES THEREOF | INTERFACE BIOLOGICS INCORPORATED (CA) | 2007-12-27 | — | — | WO | disclosed |
| EP-0263956-B1 | CIS-PLATINUM COMPLEXES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | BEHRINGWERKE Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | disclosed |
| EP-0263956-A2 | Cis-Platinum complexes, method for their preparation and pharmaceuticals containing them | BEHRINGWERKE Aktiengesellschaft (DE) | 1988-04-20 | — | — | EP | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11672867-B2 | Protein-templated self-assembly of a covalent polymer network for intracellular trafficking and traceless release | CCL2, ACTB, TIA1 | KDM4E 4568/4885PKM 2079/4885HRH3 4484/4885 |
| US-20210155726-A1 | HYDROPHILIC POLYMERIC PARTICLES AND METHODS FOR MAKING AND USING SAME | CD44, CD68, MTDH | KDM4E 4697/4885PKM 1880/4885HRH3 774/4885 |
| US-20100055068-A1 | GRAFTED POLYMERS AND USES THEREOF | ALG1, CD44, PGF | KDM4E 4797/4885PKM 962/4885HRH3 3617/4885 |
| US-11572427-B2 | Hydrophilic polymeric particles and methods for making and using same | CD44, CD68, MTDH | KDM4E 4697/4885PKM 1880/4885HRH3 774/4885 |
| US-20090270598-A1 | AMPHIPHILES FOR PROTEIN SOLUBILIZATION AND STABILIZATION | STOM, PXMP4, DBI | KDM4E 3880/4885PKM 1856/4885HRH3 4362/4885 |
| US-20110269806-A1 | 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS | F13B, HABP2, F7 | KDM4E 561/4885PKM 3274/4885HRH3 1049/4885 |
| US-20230135432-A1 | POLYMERIC NANOPARTICLES AND DERIVATIVES THEREOF FOR NUCLEIC ACID BINDING AND DELIVERY | SNRPE, HNRNPAB, MTREX | KDM4E 3511/4885PKM 2481/4885HRH3 3787/4885 |
| US-20090054432-A1 | 2-(2-Hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-Carboxamidine Derivatives as Factor VIIA Inhibitors | F13B, HABP2, F7 | KDM4E 561/4885PKM 3274/4885HRH3 1049/4885 |
| US-20200282066-A1 | PROTEIN-TEMPLATED SELF-ASSEMBLY OF A COVALENT POLYMER NETWORK FOR INTRACELLULAR TRAFFICKING AND TRACELESS RELEASE | CCL2, ACTB, TIA1 | KDM4E 4568/4885PKM 2079/4885HRH3 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.