Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13897472 | 0.82 | EPHX1 (0.40) | EPHX1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL14899103 | 0.80 | ACHE (0.34) | — | |
| SCHEMBL8503644 | 0.80 | EPHX1 (0.39) | EPHX1TSHRSMN1; SMN2 | |
| SCHEMBL143580 | 0.80 | EPHX1 (0.39) | EPHX1TSHRSMN1; SMN2 | |
| SCHEMBL11136315 | 0.78 | GAA (0.42) | TSHRSMN1; SMN2ALDH1A1HSD17B10MGAM | |
| SCHEMBL141335 | 0.77 | EPHX1 (0.40) | EPHX1TSHRALDH1A1 | |
| SCHEMBL27541671 | 0.75 | EPHX1 (0.39) | EPHX1TSHRMGAMGAASI | |
| SCHEMBL477439 | 0.75 | EPHX1 (0.39) | EPHX1TSHRMGAMGAASI | |
| SCHEMBL27591240 | 0.75 | ALDH1A1 (0.36) | EPHX1TSHRSMN1; SMN2ALDH1A1MGAM | |
| SCHEMBL8503562 | 0.73 | EPHX1 (0.57) | EPHX1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886205-A | Process for producing silicon-containing isocyanate compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0864574-A2 | Process for producing silicon-containing isocyanate compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |