Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916660 | 1.00 | OPRM1 (0.50) | OPRM1SPHK1FAAHCNR1CNR2 | |
| SCHEMBL13267162 | 1.00 | OPRM1 (0.50) | OPRM1SPHK1FAAHCNR1CNR2 | |
| SCHEMBL2549074 | 1.00 | OPRM1 (0.50) | OPRM1SPHK1FAAHCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL27799431 | 0.98 | OPRM1 (0.48) | OPRM1SPHK1FAAHCNR1CNR2 | |
| SCHEMBL8511039 | 0.97 | — | — | |
| SCHEMBL941487 | 0.90 | — | — | |
| Sulfuric Acid SCHEMBL11689554 | 0.88 | TP53 (0.60) | OPRM1SPHK1FAAHCNR1CNR2 | |
| SCHEMBL5012572 | 0.79 | OPRM1 (0.48) | OPRM1SPHK1FAAHCNR1CNR2 | |
| SCHEMBL1930626 | 0.79 | OPRM1 (0.48) | OPRM1SPHK1FAAHCNR1CNR2 | |
| SCHEMBL534657 | 0.79 | OPRM1 (0.48) | OPRM1SPHK1FAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118102-A1 | IONIZABLE CATIONIC LIPID FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. (US) | 2018-06-28 | — | — | WO | disclosed |
| CN-103097324-A | Process for the direct amination of secondary alcohols with ammonia to give primary amines | EVONIK DEGUSSA GMBH | 2013-05-08 | — | — | CN | disclosed |
| US-5886175-A | TETRACYCLINE ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| US-5512553-A | PREVENTING OR TREATING BACTERIAL INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1996-04-30 | — | — | US | disclosed |