Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.49 |
| ▸ | HTR3A | P46098 | 4/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501126 | 1.00 | HTR4 (0.49) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL8500133 | 0.89 | HTR4 (0.53) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL8497984 | 0.84 | HTR4 (0.53) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL8497978 | 0.84 | HTR4 (0.53) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL6773290 | 0.84 | HTR4 (0.55) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL13036098 | 0.80 | HTR4 (0.52) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL8508412 | 0.77 | HTR4 (0.49) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL8508409 | 0.77 | HTR4 (0.49) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL8508414 | 0.77 | HTR4 (0.49) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL8828847 | 0.76 | HTR4 (0.44) | HTR4HTR3AADRA2CADRA1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784620-B1 | N-SUBSTITUTED PIPERIDINYL BICYCLIC BENZOATE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1999-12-08 | — | — | EP | disclosed |