Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA2 | P00918 | 8/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531714 | 0.78 | PTGER4 (0.45) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL7376447 | 0.76 | MAPT (0.47) | ITGB3ITGA2BMAPTKMT2A | |
| SCHEMBL8429182 | 0.76 | PTGER4 (0.44) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL8431241 | 0.75 | PTGER4 (0.43) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL7373852 | 0.75 | ITGB3 (0.50) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL6366657 | 0.75 | MAPT (0.46) | CA1CA2MAPTKMT2A | |
| SCHEMBL8428884 | 0.74 | ITGB3 (0.42) | ITGB3ITGA2BCA1CA2CA12 | |
| SCHEMBL8531192 | 0.74 | PTGER4 (0.48) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL7378803 | 0.73 | ITGB3 (0.50) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL8501517 | 0.72 | PFKFB3 (0.46) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1999-01-13 | — | — | EP | claimed |
| WO-1997036862-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |