SCHEMBL8501260

SCHEMBL8501260

Cc1ccccc1S(=O)(=O)Oc1ccc(-c2cccc3c2Cc2ccccc2-3)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
ATM Q13315 1/20 0.43
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
GAA P10253 1/20 0.39
HTR6 P50406 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
PNMT P11086 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8500027 0.84 CYP1A2 (0.40) POLBMEN1KMT2AESR1ESR2
SCHEMBL8501629 0.82 MEN1 (0.40) POLBMEN1KMT2AESR1ESR2
SCHEMBL8498900 0.80 MEN1 (0.38) POLBMEN1KMT2AESR1ESR2
SCHEMBL6828592 0.74 ABL1 (0.50) MEN1KMT2AATMGAANPC1
SCHEMBL21358352 0.72 PNMT (0.47) POLBMEN1KMT2AGAANPC1
SCHEMBL6912873 0.72 POLB (0.62) POLBMEN1KMT2AESR1ESR2
SCHEMBL29776988 0.72 POLB (0.62) POLBMEN1KMT2AESR1ESR2
SCHEMBL7461046 0.71 ALPL (0.41) MEN1KMT2AGAAHTR6NPC1
SCHEMBL28846439 0.71 GSTP1 (0.47) NPC1RAB9APNMT
SCHEMBL8499639 0.71 ALPL (0.40) MEN1KMT2AGAAHTR6NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956312-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR Corporation (JP) 1999-11-17 EP disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed