Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642765 | 0.81 | XPO1 (0.35) | POLQALDH1A1ATMMEN1KMT2A | |
| SCHEMBL8396125 | 0.81 | RXRA (0.42) | POLQATMMRGPRX4SGMS2EPHX2 | |
| SCHEMBL8648030 | 0.77 | LIPE (0.45) | MRGPRX4LIPESMN1; SMN2LMNA | |
| SCHEMBL8398044 | 0.77 | FFAR1 (0.42) | MRGPRX4LIPEMAOAMAOB | |
| SCHEMBL8395436 | 0.76 | MCL1 (0.45) | ALDH1A1MRGPRX4MAOB | |
| SCHEMBL8399143 | 0.76 | MAOB (0.39) | MEN1KMT2AMAOAMAOBSMN1; SMN2 | |
| SCHEMBL8398978 | 0.76 | MRGPRX4 (0.51) | L3MBTL1ALDH1A1MRGPRX4GAASMN1; SMN2 | |
| SCHEMBL8645607 | 0.76 | EPHX2 (0.34) | POLQKMT2ASGMS2EPHX2MAOA | |
| SCHEMBL8396086 | 0.75 | TP53 (0.47) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8396361 | 0.75 | ANO1 (0.45) | MRGPRX4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856573-A | Process for producing 2-(2-hydroxymethylphenyl)acetamide derivative and intermediate for the production thereof | SHIONOGI & CO., LTD (JP) | 1999-01-05 | — | — | US | disclosed |