Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 6/20 | 0.49 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7612044 | 0.93 | SMN1; SMN2 (0.70) | KDM4EMEN1NPC1LMNAMAPT | |
| Dimethylamine SCHEMBL7142653 | 0.93 | SMN1; SMN2 (0.70) | KDM4EMEN1NPC1LMNAMAPT | |
| Methylamine SCHEMBL7145892 | 0.90 | SMN1; SMN2 (0.70) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL27435146 | 0.89 | SMN1; SMN2 (0.74) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL7141554 | 0.89 | MAPT (0.74) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL8500494 | 0.89 | LMNA (0.55) | KDM4EMEN1NPC1LMNAMAPT | |
| Dimethylamine SCHEMBL7146086 | 0.86 | CA2 (0.65) | MAPTSMN1; SMN2CA2CA1CA12 | |
| SCHEMBL7141516 | 0.83 | LMNA (0.60) | KDM4EMEN1NPC1LMNAMAPT | |
| Propionamide SCHEMBL27520984 | 0.82 | LMNA (0.59) | KDM4EMEN1NPC1LMNAMAPT | |
| Tert-Butylamine SCHEMBL7141555 | 0.81 | CA2 (0.63) | KDM4EMEN1MAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964849-A1 | SULFONYL UREA DERIVATIVES AND THEIR USE IN THE CONTROL OF INTERLEUKIN-1 ACTIVITY | PFIZER INC. (US) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998032733-A1 | SULFONYL UREA DERIVATIVES AND THEIR USE IN THE CONTROL OF INTERLEUKIN-1 ACTIVITY | PFIZER INC. (US) | 1998-07-30 | — | — | WO | disclosed |