SCHEMBL850149

SCHEMBL850149

Nc1c(C(=O)O)ncn1C1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATIC P31939 3/20 0.84
FBP1 P09467 2/20 0.84
DNPH1 O43598 4/20 0.61
TAS1R3 Q7RTX0 3/20 0.61
TAS1R1 Q7RTX1 3/20 0.61
P2RY1 P47900 2/20 0.61
PRKAB2 O43741 1/20 0.61
TRPM2 O94759 1/20 0.61
LDHA P00338 1/20 0.61
ADRB2 P07550 1/20 0.61
SRC P12931 1/20 0.61
ADORA1 P30542 1/20 0.61
P2RY2 P41231 1/20 0.61
PRKAG1 P54619 1/20 0.61
PRKAA2 P54646 1/20 0.61
PDE4D Q08499 1/20 0.61
KCNH2 Q12809 1/20 0.61
PRKAA1 Q13131 1/20 0.61
PDE3A Q14432 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4366531 1.00 ATIC (0.84) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL4359558 1.00 ATIC (0.84) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL29602059 1.00 ATIC (0.84) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL4366540 1.00 ATIC (0.84) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL20276955 0.91 ATIC (1.00) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL4359472 0.91 ATIC (1.00) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL1230585 0.91 ATIC (1.00) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL849848 0.91 ATIC (1.00) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL20134003 0.91 ATIC (1.00) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL1230589 0.91 ATIC (1.00) ATICFBP1DNPH1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100143911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-06-10 US claimed
EP-2097743-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS Korea Advanced Institute of Science and Technology (KR) 2009-09-09 EP claimed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 WO claimed
US-20240018559-A1 GENETICALLY ENGINEERED BACTERIUM CAPABLE OF PRODUCING CYTOKININS WITH ISOPRENOID SIDE CHAINS ACIES BIO D.O.O. (SI) 2024-01-18 US disclosed
CN-113603721-B Method for synthesizing SAICAR 重庆文理学院 2023-12-01 CN disclosed
EP-4251745-A1 GENETICALLY ENGINEERED BACTERIUM CAPABLE OF PRODUCING CYTOKININS WITH ISOPRENOID SIDE CHAINS Acies Bio d.o.o. (SI) 2023-10-04 EP disclosed
CN-116832017-A Application of cinnamaldehyde 中国科学院昆明动物研究所 2023-10-03 CN disclosed
WO-2022112509-A1 GENETICALLY ENGINEERED BACTERIUM CAPABLE OF PRODUCING CYTOKININS WITH ISOPRENOID SIDE CHAINS ACIES BIO D.O.O. (SI) 2022-06-02 WO disclosed
EP-4006139-A1 GENETICALLY ENGINEERED BACTERIUM CAPABLE OF PRODUCING CYTOKININS WITH ISOPRENOID SIDE CHAINS Acies Bio d.o.o. (SI) 2022-06-01 EP disclosed
WO-2022095809-A1 NEW APPLICATION OF COMPOUNDS INFLUENCING SAICAR EXPRESSION 广州君赫生物科技有限公司 2022-05-12 WO disclosed
CN-113603721-A Method for synthesizing SAICAR 重庆文理学院 2021-11-05 CN disclosed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 WO disclosed
EP-1887081-A2 DNA Sequences Ceres Incorporated (US) 2008-02-13 EP disclosed
US-20070298484-A1 Method and Device for Thermal Conditioning of a Cell INSILICO BIOTECHNOLOGY GMBH (DE) 2007-12-27 US disclosed
EP-1720976-A1 METHOD AND DEVICE FOR THERMAL CONDITIONING OF A CELL Insilico Biotechnology Gmbh (DE) 2006-11-15 EP disclosed
EP-1586645-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2005-10-19 EP disclosed
WO-2005083054-A1 METHOD AND DEVICE FOR THERMAL CONDITIONING OF A CELL INSILICO BIOTECHNOLOGY GMBH (DE) 2005-09-09 WO disclosed
US-20030229916-A1 Phosphoribosylaminoimidazole carboxylase E. I. DU PONT DE NEMOURS AND COMPANY 2003-12-11 US disclosed
EP-1059354-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2000-12-13 EP disclosed
EP-1033405-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2000-09-06 EP disclosed