Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 3/20 | 0.84 |
| ▸ | FBP1 | P09467 | 2/20 | 0.84 |
| ▸ | DNPH1 | O43598 | 4/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.61 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.61 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.61 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.61 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.61 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366531 | 1.00 | ATIC (0.84) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL850149 | 1.00 | ATIC (0.84) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL29602059 | 1.00 | ATIC (0.84) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL4366540 | 1.00 | ATIC (0.84) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL20276955 | 0.91 | ATIC (1.00) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL4359472 | 0.91 | ATIC (1.00) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL1230585 | 0.91 | ATIC (1.00) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL849848 | 0.91 | ATIC (1.00) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL20134003 | 0.91 | ATIC (1.00) | ATICFBP1DNPH1TAS1R3TAS1R1 | |
| SCHEMBL1230589 | 0.91 | ATIC (1.00) | ATICFBP1DNPH1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250037787-A1 | CONCENTRATION BOUNDS IN LARGE NETWORKS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-01-30 | — | — | US | disclosed |
| US-11766412-B2 | Methods of treating or alleviating adenylosuccinatelyase (ADSL) deficiency using spermidine or a pharmaceutically acceptable salt of spermidine | GENEHEAL BIOTECHNOLOGY CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| US-11766412-B2 | Methods of treating or alleviating adenylosuccinatelyase (ADSL) deficiency using spermidine or a pharmaceutically acceptable salt of spermidine | GENEHEAL BIOTECHNOLOGY CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| US-11684593-B2 | Applications of spermine and its derivative in preparation of antitumor drug | GENEHEAL BIOTECHNOLOGY CO., LTD. (CN) | 2023-06-27 | — | — | US | disclosed |
| US-11684593-B2 | Applications of spermine and its derivative in preparation of antitumor drug | GENEHEAL BIOTECHNOLOGY CO., LTD. (CN) | 2023-06-27 | — | — | US | disclosed |
| EP-3976799-A2 | MULTIPLY AUXOTROPHIC CELL LINE FOR THE PRODUCTION OF RECOMBINANT PROTEINS AND METHODS THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-04-06 | — | — | EP | disclosed |
| US-20220089775-A1 | MULTIPLY AUXOTROPHIC CELL LINE FOR THE PRODUCTION OF RECOMBINANT PROTEINS AND METHODS THEREOF | UNIV COLUMBIA (US) | 2022-03-24 | — | — | US | disclosed |
| EP-3562825-B1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2022-02-16 | — | — | EP | disclosed |
| EP-3562824-B1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2022-01-26 | — | — | EP | disclosed |
| US-20210008012-A1 | NOVEL APPLICATIONS OF DISULFIRAM AND DERIVATIVES THEREOF | GENEHEAL BIOTECHNOLOGY CO., LTD. (CN) | 2021-01-14 | — | — | US | disclosed |
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | INSTITUTE OF CATALYSIS (CSIC) (ES) | 2012-09-13 | — | — | US | disclosed |
| WO-2010105851-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-23 | — | — | WO | disclosed |
| US-20090186358-A1 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof | WYETH (US) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210008012-A1 | NOVEL APPLICATIONS OF DISULFIRAM AND DERIVATIVES THEREOF | ADSL, ADSS2, ACACB | ATIC 471/4885FBP1 520/4885DNPH1 2838/4885 |
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | SI, GUSB, MPI | ATIC 835/4885FBP1 689/4885DNPH1 11/4885 |
| US-11766412-B2 | Methods of treating or alleviating adenylosuccinatelyase (ADSL) deficiency using spermidine or a pharmaceutically acceptable salt of spermidine | ADSL, ADSS2, SRM | ATIC 146/4885FBP1 316/4885DNPH1 1661/4885 |
| US-11684593-B2 | Applications of spermine and its derivative in preparation of antitumor drug | SRM, SMS, SMOX | ATIC 290/4885FBP1 284/4885DNPH1 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.