Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.46 |
| ▸ | ADH1A | P07327 | 2/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26529454 | 0.83 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3667042 | 0.80 | ADH1B (0.41) | ADH1BADH1AADH1CGAAMGAM | |
| SCHEMBL11387135 | 0.78 | ALDH1A1 (0.40) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4269571 | 0.77 | ADH1B (0.43) | ADH1BADH1AADH1CGAAPKM | |
| SCHEMBL14102105 | 0.77 | GAA (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5567613 | 0.76 | MGAM (0.43) | ADH1BADH1AADH1CGAAMGAM | |
| SCHEMBL27880755 | 0.76 | ADH1B (0.38) | ADH1BADH1AADH1CGAAMGAM | |
| SCHEMBL12150025 | 0.75 | CYP2C19 (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL26529043 | 0.75 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11232368 | 0.74 | CYP1A2 (0.42) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939398-A | ANTIATHEROSCLEROSIS AGENTS | PFIZER INC. (US) | 1999-08-17 | — | — | US | disclosed |