Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13532440 | 0.87 | PKM (0.44) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL15894569 | 0.87 | PKM (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL29872559 | 0.84 | LMNA (0.68) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL214157 | 0.84 | LMNA (0.68) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL30485784 | 0.82 | CYP2D6 (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL9556365 | 0.82 | LMNA (0.65) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL1176482 | 0.82 | CYP2D6 (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL10051867 | 0.80 | LMNA (0.52) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL4058106 | 0.79 | LMNA (0.45) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL3824782 | 0.78 | LMNA (0.61) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784610-B1 | HYDROCYANATION PROCESS AND MULTIDENTATE PHOSPHITE AND NICKEL CATALYST COMPOSITION THEREFOR | DU PONT (US) | 1999-02-10 | — | — | EP | disclosed |
| US-5663369-A | HYDROCYANATION OF BUTADIENE TO FORM PENTENENITRILE AND FORMING ADIPONITRILE BY PENTENITRILE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| US-5512696-A | HYDROCYANATION OF ALIPHATIC MONOETHYLENICALLY UNSATURATEDCOMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |