Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.52 |
| ▸ | CHRNG | P07510 | 2/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.52 |
| ▸ | CHRND | Q07001 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Phenylalanine SCHEMBL8501652 | 1.00 | OPRD1 (0.53) | OPRD1OPRM1OPRK1SLC7A5CHRNA1 | |
| Tyrosine SCHEMBL5159832 | 0.86 | SLC7A5 (0.71) | OPRD1OPRM1OPRK1SLC7A5 | |
| D-Phenylalanine SCHEMBL8498797 | 0.85 | ACE (0.50) | OPRD1OPRM1OPRK1ITGB3ITGA2B | |
| SCHEMBL4162323 | 0.85 | MME (0.63) | CHRNA1CHRNGCHRNB1CHRNDITGB3 | |
| SCHEMBL27840664 | 0.85 | MME (0.63) | CHRNA1CHRNGCHRNB1CHRNDITGB3 | |
| SCHEMBL4160723 | 0.85 | MME (0.63) | CHRNA1CHRNGCHRNB1CHRNDITGB3 | |
| SCHEMBL4160727 | 0.85 | MME (0.63) | CHRNA1CHRNGCHRNB1CHRNDITGB3 | |
| SCHEMBL4162326 | 0.85 | MME (0.63) | CHRNA1CHRNGCHRNB1CHRNDITGB3 | |
| Acetyl Tyrosine SCHEMBL7688897 | 0.82 | FOLH1 (0.58) | SLC7A5ITGB3ITGA2BACEGRIA1 | |
| Tyrosine SCHEMBL1585042 | 0.82 | SLC7A5 (0.77) | OPRM1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929574-A1 | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998008868-A1 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 1998-03-05 | — | — | WO | claimed |