Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.74 |
| ▸ | TGM2 | P21980 | 1/20 | 0.73 |
| ▸ | KRAS | P01116 | 7/20 | 0.67 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.66 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.63 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.62 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.62 |
| ▸ | HINT1 | P49773 | 1/20 | 0.61 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.61 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28275952 | 0.97 | NT5E (0.75) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL574773 | 0.97 | NT5E (0.74) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL27819299 | 0.97 | NT5E (0.74) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL28222628 | 0.97 | NT5E (0.74) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL4366555 | 0.96 | NT5E (0.73) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL28597191 | 0.96 | NT5E (0.73) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL5994438 | 0.95 | NT5E (0.72) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL5172347 | 0.95 | TGM2 (0.81) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL1096040 | 0.95 | TGM2 (0.81) | NT5ETGM2KRASFUT5IMPDH2 | |
| SCHEMBL20850061 | 0.94 | NT5E (0.71) | NT5ETGM2KRASFUT5IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945509-A | A POLYPEPTIDE THAT CODES FOR A MEMBRANE PROTEIN INVOLVED IN NEUROTRANSMISSION; THERAPY AND DIAGNOSIS OF NERVOUS SYSTEMDISORDERS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1999-08-31 | — | — | US | disclosed |
| US-5739291-A | MONOCLONAL ANTIBODY BINDS TO GENETIC ENGINEERED PROTEIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-04-14 | — | — | US | disclosed |
| US-5202257-A | Pure DNA which is capable of hybridizing with receptor polynucleotides under mild conditions | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1993-04-13 | — | — | US | disclosed |