Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.73 |
| ▸ | TGM2 | P21980 | 1/20 | 0.72 |
| ▸ | KRAS | P01116 | 4/20 | 0.68 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.67 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.64 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.64 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.64 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.63 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.62 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.62 |
| ▸ | HINT1 | P49773 | 1/20 | 0.61 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.60 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.60 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597191 | 1.00 | NT5E (0.73) | NT5ETGM2KRASFUT5P2RY6 | |
| SCHEMBL27819299 | 0.99 | NT5E (0.74) | NT5ETGM2KRASFUT5P2RY6 | |
| SCHEMBL574773 | 0.99 | NT5E (0.74) | NT5ETGM2KRASFUT5P2RY6 | |
| SCHEMBL28222628 | 0.99 | NT5E (0.74) | NT5ETGM2KRASFUT5P2RY6 | |
| SCHEMBL28275952 | 0.98 | NT5E (0.75) | NT5ETGM2KRASFUT5P2RY6 | |
| SCHEMBL27688115 | 0.97 | NT5E (0.77) | NT5ETGM2KRASFUT5P2RY6 | |
| SCHEMBL8501729 | 0.96 | NT5E (0.74) | NT5ETGM2KRASFUT5P2RY6 | |
| SCHEMBL5994438 | 0.94 | NT5E (0.72) | NT5ETGM2KRASFUT5P2RY6 | |
| SCHEMBL376139 | 0.94 | TGM2 (0.81) | NT5ETGM2KRASFUT5P2RY6 | |
| Gtp SCHEMBL5809658 | 0.94 | TGM2 (0.81) | NT5ETGM2KRASFUT5P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186358-A1 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof | WYETH (US) | 2009-07-23 | — | — | US | disclosed |