Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501746 | 0.82 | TLR8 (0.41) | TLR8TLR7PDPK1ADRB2LOXL2 | |
| SCHEMBL8499704 | 0.82 | TLR8 (0.41) | TLR8TLR7PDPK1ADRB2LOXL2 | |
| SCHEMBL25457211 | 0.79 | RAB9A (0.53) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL9959860 | 0.78 | TLR8 (0.47) | TLR8TLR7PDPK1ADRB2LOXL2 | |
| SCHEMBL12052868 | 0.77 | POLB (0.51) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL5306795 | 0.75 | RAB9A (0.48) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL11221691 | 0.73 | PDE3B (0.49) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL13041695 | 0.73 | RAB9A (0.64) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL5307575 | 0.72 | NISCH (0.51) | TLR8TLR7MEN1NPC1POLB | |
| SCHEMBL8094750 | 0.72 | PDPK1 (0.42) | TLR8TLR7PDPK1ADRB2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946559-A2 | IMIDAZOPYRIDAZINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028299-A2 | IMIDAZOPYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-02 | — | — | WO | disclosed |