Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495872 | 1.00 | L3MBTL1 (0.52) | L3MBTL1MTNR1AMTNR1BHDAC1HDAC2 | |
| SCHEMBL8496083 | 0.88 | TP53 (0.51) | FAAH | |
| SCHEMBL8500341 | 0.85 | L3MBTL1 (0.49) | L3MBTL1MTNR1AMTNR1BHDAC1HDAC2 | |
| SCHEMBL8496262 | 0.80 | L3MBTL1 (0.44) | L3MBTL1MTNR1AMTNR1BHDAC1HDAC2 | |
| SCHEMBL8500379 | 0.80 | S1PR1 (0.52) | — | |
| SCHEMBL8496223 | 0.79 | CNR1 (0.53) | PPARA | |
| SCHEMBL8496714 | 0.78 | S1PR1 (0.56) | — | |
| SCHEMBL8496350 | 0.74 | ALDH1A1 (0.42) | L3MBTL1 | |
| SCHEMBL8496883 | 0.74 | KCNA3 (0.55) | HDAC1HDAC2PPARAKCNA3RECQL | |
| SCHEMBL8497490 | 0.74 | KCNA3 (0.55) | HDAC1HDAC2PPARAKCNA3RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |