Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501773 | 0.76 | KDM4E (0.40) | ALDH1A1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL21311972 | 0.72 | — | — | |
| SCHEMBL11050912 | 0.72 | — | — | |
| SCHEMBL2719762 | 0.71 | PRMT6 (0.63) | PRMT6THRBTP53ALDH1A1LMNA | |
| SCHEMBL9971312 | 0.71 | ALDH1A1 (0.58) | PRMT6THRBTP53ALDH1A1NPC1 | |
| SCHEMBL23879711 | 0.69 | PRMT6 (0.61) | PRMT6THRBTP53ALDH1A1LMNA | |
| SCHEMBL23432958 | 0.69 | PRMT6 (0.61) | PRMT6THRBTP53ALDH1A1LMNA | |
| SCHEMBL4413504 | 0.69 | PRMT6 (0.55) | PRMT6THRBTP53ALDH1A1LMNA | |
| SCHEMBL3306074 | 0.68 | IKBKB (0.41) | ALDH1A1RAB9AMEN1KMT2AGAA | |
| SCHEMBL18355168 | 0.68 | PRMT6 (0.59) | PRMT6THRBTP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939398-A | ANTIATHEROSCLEROSIS AGENTS | PFIZER INC. (US) | 1999-08-17 | — | — | US | disclosed |