Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666005 | 0.94 | NPY5R (0.36) | NPY5RKDM4DRETPARP1PARP2 | |
| SCHEMBL8482320 | 0.93 | NPY5R (0.37) | NPY5RKDM4DRETPARP1PARP2 | |
| SCHEMBL8504375 | 0.87 | CCR3 (0.38) | DRD2 | |
| SCHEMBL8504386 | 0.83 | NTRK1 (0.34) | ENPP2KDM4DRETNTRK1DPP4 | |
| SCHEMBL8668033 | 0.81 | CCR3 (0.41) | NPY5RRETDRD2 | |
| SCHEMBL8483741 | 0.81 | CCR3 (0.44) | — | |
| SCHEMBL8669574 | 0.79 | KDM4D (0.36) | NPY5RKDM4DRETNTRK1DPP4 | |
| SCHEMBL8484139 | 0.77 | NTRK1 (0.36) | NPY5RKDM4DRETPARP1PARP2 | |
| SCHEMBL8501233 | 0.73 | NPSR1 (0.36) | DRD2 | |
| SCHEMBL8664869 | 0.72 | SMPD3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |