Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669574 | 0.94 | KDM4D (0.36) | NTRK1RETKDM4DDPP4 | |
| SCHEMBL8484139 | 0.93 | NTRK1 (0.36) | NTRK1RETKDM4D | |
| SCHEMBL8503043 | 0.83 | NPY5R (0.33) | NTRK1RETENPP2KDM4DDPP4 | |
| SCHEMBL8665212 | 0.81 | CCR3 (0.39) | RET | |
| SCHEMBL8504363 | 0.81 | KCNA5 (0.30) | — | |
| SCHEMBL8479703 | 0.80 | CCR3 (0.42) | RET | |
| SCHEMBL8666005 | 0.79 | NPY5R (0.36) | RETKDM4D | |
| SCHEMBL8482320 | 0.78 | NPY5R (0.37) | NTRK1RETKDM4D | |
| SCHEMBL8484431 | 0.77 | L3MBTL1 (0.35) | — | |
| SCHEMBL8479385 | 0.74 | DPP4 (0.38) | DPP4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |