Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503957 | 1.00 | KMT2A (0.45) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL8773724 | 0.74 | ALDH1A1 (0.43) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL5903600 | 0.74 | ALDH1A1 (0.43) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL26326088 | 0.73 | AKT1 (0.50) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL8352132 | 0.72 | AKT1 (0.46) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL18707238 | 0.72 | HDAC3 (0.45) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL18706832 | 0.72 | HDAC3 (0.45) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL18707214 | 0.72 | HDAC3 (0.45) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL5170828 | 0.71 | CTSS (0.48) | KMT2AL3MBTL1MEN1HTTCTSS | |
| SCHEMBL3819098 | 0.71 | AKT1 (0.52) | KMT2AL3MBTL1MEN1HTTCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872298-A | Method of preparing intermediates for retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5872299-A | Method of preparing intermediates for retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5831117-A | ACID SALTS | G. D. SEARLE & CO. (US) | 1998-11-03 | — | — | US | disclosed |