SCHEMBL850422

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5436067	0.82	KMT2A (0.47)	HDAC1HDAC6KMT2AALDH1A1MAPT
	SCHEMBL15262472	0.81	KDM4E (0.51)	ALDH1A1MAPTKDM4EHPGDLMNA
	SCHEMBL11210850	0.81	KMT2A (0.57)	HDAC1HDAC6KMT2AALDH1A1MAPT
	SCHEMBL16302226	0.81	KMT2A (0.46)	HDAC1HDAC6KMT2AALDH1A1MAPT
	SCHEMBL15926181	0.80	HDAC1 (0.50)	HDAC1HDAC6KMT2AALDH1A1MAPT
	SCHEMBL27457692	0.79	KMT2A (0.44)	HDAC1HDAC6KMT2AALDH1A1MAPT
	SCHEMBL27474959	0.79	ALDH1A1 (0.49)	HDAC1HDAC6KMT2AALDH1A1MAPT
	SCHEMBL22709990	0.78	KMT2A (0.50)	HDAC1HDAC6KMT2AALDH1A1MAPT
	SCHEMBL17117530	0.78	KMT2A (0.50)	HDAC1HDAC6KMT2AALDH1A1MAPT
	SCHEMBL5724755	0.77	ALDH1A1 (0.55)	HDAC1HDAC6KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.