Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628536 | 1.00 | KDM4E (0.40) | KDM4EDAOALDH1A1MAPTMEN1 | |
| SCHEMBL5439441 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29513087 | 0.70 | SLC9A1 (0.63) | KDM4EDAOALDH1A1MAPTMEN1 | |
| SCHEMBL15697558 | 0.70 | SLC9A1 (0.63) | KDM4EDAOALDH1A1MAPTMEN1 | |
| SCHEMBL8507142 | 0.68 | RXFP1 (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15516976 | 0.67 | MCL1 (0.44) | KDM4EDAOALDH1A1MAPTMEN1 | |
| SCHEMBL9452283 | 0.67 | HPGD (0.57) | KDM4EDAOALDH1A1MAPTMEN1 | |
| SCHEMBL31628357 | 0.67 | KIF11 (0.55) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8506970 | 0.67 | KIF11 (0.55) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2993953 | 0.65 | KDM4E (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750621-B1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1999-07-21 | — | — | EP | claimed |