Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 3/20 | 0.60 |
| ▸ | PGR | P06401 | 10/20 | 0.59 |
| ▸ | AR | P10275 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502593 | 0.94 | ABCB11 (0.60) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL8502794 | 0.92 | ABCB11 (0.59) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL8504525 | 0.91 | ABCB11 (0.58) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL8505295 | 0.90 | ABCB11 (0.61) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL7209821 | 0.88 | ABCB11 (0.59) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL7204614 | 0.86 | ABCB11 (0.60) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL10705001 | 0.85 | ABCB11 (0.60) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL7210548 | 0.85 | ABCB11 (0.62) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL10707938 | 0.85 | ABCB11 (0.58) | ABCB11PGRARCYP3A4NR3C1 | |
| SCHEMBL8502873 | 0.84 | PGR (0.57) | ABCB11PGRARCYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981517-A | FOR TREATING INFLAMMATIONS OF EYES, EARS, SKINS, INTESTINES, MOUTHS, ASTHMA, AND ARTHRITIS IN ANIMALS | SOFT DRUGS, INC. (US) | 1999-11-09 | — | — | US | disclosed |