Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | CCR8 | P51685 | 2/20 | 0.31 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669816 | 0.70 | AR (0.38) | CTSD | |
| SCHEMBL8503831 | 0.70 | MAPT (0.39) | CTSD | |
| SCHEMBL637824 | 0.62 | KDM4E (0.47) | CTSD | |
| SCHEMBL8586447 | 0.59 | KMT2A (0.39) | — | |
| SCHEMBL12354513 | 0.58 | CA12 (0.66) | ACSS2 | |
| SCHEMBL9014003 | 0.58 | CCR1 (0.80) | CCR1CCR5CCR8 | |
| SCHEMBL9014019 | 0.58 | CCR1 (0.80) | CCR1CCR5CCR8 | |
| SCHEMBL14554394 | 0.58 | CCR1 (0.80) | CCR1CCR5CCR8 | |
| SCHEMBL10333049 | 0.58 | CCR1 (0.51) | CCR1CCR5CCR8 | |
| Hydrochloric Acid SCHEMBL7181558 | 0.58 | ACSS2 (0.50) | AGPAT2ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998445-A | PEPTIC ULCERS | EISAI CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0654471-B1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and process for preparing the same | EISAI CO LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0475456-B1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | EISAI CO LTD (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0268956-A2 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1988-06-01 | — | — | EP | disclosed |