Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18466133 | 0.88 | CHRNA7 (0.49) | CHRNA7CHRNB2CHRNA4L3MBTL1MEN1 | |
| SCHEMBL20671931 | 0.84 | CHRNA7 (0.45) | CHRNA7CHRNB2CHRNA4L3MBTL1MEN1 | |
| SCHEMBL18617707 | 0.81 | CHRNB2 (0.49) | DRD2DRD3CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL8219698 | 0.81 | CHRNA7 (0.45) | CHRNA7CHRNB2CHRNA4L3MBTL1MEN1 | |
| SCHEMBL8276784 | 0.81 | CHRNB2 (0.45) | CHRNA7CHRNB2CHRNA4L3MBTL1MEN1 | |
| SCHEMBL27527125 | 0.77 | MEN1 (0.50) | CHRNA7CHRNB2CHRNA4L3MBTL1MEN1 | |
| SCHEMBL8221503 | 0.77 | PRMT6 (0.45) | DRD2CHRNA7CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL8212158 | 0.77 | PRMT6 (0.49) | DRD2CHRNA7CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL18616367 | 0.76 | CHRNB2 (0.41) | CHRNA7CHRNB2CHRNA4L3MBTL1MEN1 | |
| SCHEMBL4379176 | 0.76 | DRD3 (0.67) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |