Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184663 | 0.82 | NR4A2 (0.47) | HTTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL7782003 | 0.82 | NCEH1 (0.45) | HTTKDM4EALDH1A1HPGDSLC6A3 | |
| SCHEMBL7781995 | 0.82 | NCEH1 (0.45) | HTTKDM4EALDH1A1HPGDSLC6A3 | |
| SCHEMBL9331693 | 0.80 | NR4A2 (0.47) | HTTKDM4EALDH1A1SLC6A3POLB | |
| SCHEMBL7791053 | 0.76 | TSHR (0.47) | HTTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL7789707 | 0.75 | BACE1 (0.40) | KDM4EALDH1A1HPGDSLC6A3POLB | |
| SCHEMBL15653347 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1HPGDSLC6A3POLB | |
| SCHEMBL20123231 | 0.73 | KDM4E (0.52) | HTTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL29963395 | 0.73 | NCEH1 (0.53) | HTTKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL10395178 | 0.73 | GAA (0.41) | HTTKDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0954522-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG Industries Ohio, Inc. (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0954522-A4 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG IND OHIO INC (US) | 1999-06-21 | — | — | EP | disclosed |
| WO-1997021698-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1997-06-19 | — | — | WO | disclosed |