Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652416 | 0.88 | KDM4E (0.50) | BACE1KDM4EHSD17B10GAAPOLB | |
| SCHEMBL6651295 | 0.86 | BACE1 (0.44) | BACE1KDM4EHSD17B10GAAGLA | |
| SCHEMBL9331693 | 0.84 | NR4A2 (0.47) | NR4A2KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7789707 | 0.84 | BACE1 (0.40) | NR4A2BACE1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL6383895 | 0.83 | BACE1 (0.51) | NR4A2BACE1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL8504792 | 0.82 | HTT (0.44) | KDM4ECYP1A2CYP2C9HSD17B10KMT2A | |
| SCHEMBL8510685 | 0.81 | PLA2G2A (0.51) | NR4A2BACE1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL6172886 | 0.80 | NR4A2 (0.51) | NR4A2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10395178 | 0.80 | GAA (0.41) | NR4A2BACE1KDM4EHSD17B10GAA | |
| SCHEMBL6652172 | 0.79 | CES2 (0.54) | KDM4EHSD17B10GAAGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087304-A | ANTIARRHYTHMIC PHARMACEUTICALS HAVING A CARDIOPROTECTIVE COMPONENT FOR INFARCT PROPHYLAXIS AND INFARCT TREATMENT AND FOR THE TREATMENT OF ANGINA PECTORIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-07-11 | — | — | US | disclosed |