Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17240274 | 0.83 | MAPT (0.50) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL3741758 | 0.83 | KDM4E (0.60) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL2470133 | 0.81 | LMNA (0.55) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL7786707 | 0.81 | LMNA (0.44) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL7791053 | 0.81 | TSHR (0.47) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL244414 | 0.80 | KDM4E (0.45) | KDM4EHSD17B10ALDH1A1HPGDNPSR1 | |
| SCHEMBL24101354 | 0.77 | PLK1 (0.70) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL7677649 | 0.77 | KDM4E (0.57) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL5551334 | 0.76 | PLK1 (0.48) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL13659570 | 0.75 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203161-B1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | UNIV INDIANA RES & TECH CORP (US) | 2018-05-09 | — | — | EP | disclosed |